招聘简介：

在旧金山加利福尼亚大学Nakamura实验室，鼓励有兴趣研究肿瘤转化分子机制的翻译重点。Jean Nakamura博士，首席研究员，是癌症中心的内科医生和执业肿瘤学家。中村研究计划的一个核心目标是为肿瘤领域的应用开发创新的诊断和治疗策略，为此，实验室在基因组学、代谢、临床前实验和成像领域与多个跨学科、翻译研究小组合作。

我们的实验室位于加州大学旧金山分校MissionBay校区的Helen Diller家庭癌症研究大楼。作为UCSF最新的校区，Mission Bay校区是一个充满活力、科学活力的环境，拥有众多共享资源，支持前沿研究。在这个高度协作、多学科的环境中，我们对小鼠和人类肿瘤进行了整合的基因组和功能分析，以研究致癌的分子机制。该实验室在研究不同恶性肿瘤的信号转导通路作为治疗靶点和建立小鼠体内肿瘤发生模型方面具有特殊的专长。合适的候选人是将获得或最近获得博士学位的个人。我们研究体外和体内模型以及原发性人类癌症标本，主要目的是将我们的研究结果转化为治疗和预防的研究试验。

英文原文：

Individuals interested in investigating the molecular mechanisms of tumorigenesis with a translational emphasis are encouraged to apply for postdoctoral training in the Nakamura laboratory at the University of California San Francisco. Dr. Jean Nakamura, the Principal Investigator, is a physician-scientist and a practicing oncologist in the Cancer Center. A core objective of the Nakamura research program is to develop innovative diagnostic and therapeutic strategies for applications in oncology, and to this end, the lab collaborates with multiple interdisciplinary, translational research groups in the areas of genomics, metabolism, pre-clinical experimentation and imaging.

Our laboratory is located in the Helen Diller Family Cancer Research Building at the Mission Bay Campus of UCSF. The newest of the UCSF campuses, the Mission Bay campus is a dynamic, scientifically vibrant environment with numerous shared resources to support cutting-edge research. In this highly collaborative, multidisciplinary environment, we have integrated genomic and functional analysis of mouse and human tumors to investigate molecular mechanisms driving cancer. The lab has particular expertise in studying signal transduction pathways in diverse malignancies as therapeutic targets and developing mouse models of in vivo tumorigenesis. Appropriate candidates are individuals who will be awarded or recently awarded PhDs. We study in vitro and in vivo models as well as primary human cancer specimens and a major goal is to translate our findings into investigational trials for both therapeutics and prevention.

The postdoctoral fellow will be expected to develop a leadership role in a project and contribute as a collaborator to other efforts. Areas of study in our laboratory include cancer metabolism, kinase signaling, response to ionizing radiation and mechanisms of cancer resistance to therapy. Individuals having research experience in cell biology, biochemistry, kinase signaling, cellular metabolism and/or use of mammalian model organisms are sought. The postdoctoral fellow will have the opportunity to be involved in highly collaborative research involving multiple research groups (clinical and basic science) within UCSF as well as nationally and internationally. Strong communication skills (written and verbal) in English are mandatory.

Career development opportunities include development of scientific presentation and writing skills, development of leadership role in collaborative research, as well as paper presentation at national and international meetings. A PhD and fluency in spoken and written English are required.

Send curriculum vitae and contact information for three references to Jean Nakamura, M.D., Department of Radiation Oncology, University of California, San Francisco, 1450 Third Street, Room 266, San Francisco, CA 94158. Email: Jean.nakamura@ucsf.edu. UCSF is an equal opportunity employer.