招聘简介：

·北达科他大学

职位描述

北达科他大学医学与健康科学学院，生物医学科学系，博士后研究员，职位00024672

北达科他大学医学与健康科学学院生物医学科学系（理学学士）的波特实验室正在寻找神经药理学领域的博士后研究员。被鉴定的个体将负责描述与关键表观遗传调控基因相关的炎症特征，以及与脑免疫细胞相关的信号通路，这是帕金森病（PD）进展的已知因素。从这些研究中获得的翻译知识对于发现早期PD的新的诊断生物标记物或识别潜在的治疗靶点具有临床意义，这些靶点构成了这种衰弱性疾病目前尚不清楚的潜在原因。

英文原文：

· University of North Dakota

Job Description

UNIVERSITY OF NORTH DAKOTA SCHOOL OF MEDICINE AND HEALTH SCIENCES, DEPARTMENT OF BIOMEDICAL SCIENCES, POSTDOCTORAL RESEARCH FELLOW, POSITION #00024672

The Porter laboratory in the Department of Biomedical Sciences (BSc), School of Medicine and Health Sciences (SMHS), University of North Dakota (UND), is seeking a Postdoctoral Research Fellow in the area of neuropharmacology. The identified individual will be responsible for characterizing the inflammatory profiles associated with crucial epigenetically-regulated genes and connected signaling pathways in brain immune cells, which are known contributors in the progression of Parkinson’s disease (PD). Translational knowledge obtained from these studies would be clinically significant for uncovering novel diagnostic biomarkers of early stage PD or the identification of potential therapeutic targets that constitute the as yet unknown underlying cause of this debilitating disease.

Compensation and Appointment:

Position: Postdoctoral Research Fellow,

Remuneration / Salary: up to $45,000/year + benefits commensurate with qualifications

Benefits: Includes single or family health care coverage (premiums paid for by the university), basic life insurance, EAP, retirement plan, tuition waiver. Optional benefits available: supplemental life, dental, vision, long term care insurance, flexible spending account, supplemental retirement plans.

This position is a twelve (12) month, non-tenure track, special appointment with University of North Dakota (UND) School of Medicine and Health Sciences (SMHS), Department of Biomedical Sciences.

Job Summary and Responsibilities:

The Postdoctoral Research Fellow position is part of an interdisciplinary collaboration between a group of Department Faculty members interested in utilizing immunological, biochemical and systems pharmacological approaches to investigate novel mechanisms of neurodegeneration. The identified Postdoctoral Research Fellow will be responsible for performing the experimental procedures for the following three major research activities. (1) Isolation and quality assessment of microglia from transgenic animal models; (2) Simultaneous mRNA and DNA extraction from isolated microglia for gene expression and methylation analysis using deep-sequencing techniques; and (3) Profiling of bioactive compounds secreted from isolated microglia using Fluorescent Multiplexed Bead-Based Immunoassay (FMIA) and Ultra-Performance Liquid Chromatography with Tandem Mass Spectrometry (UPLC-MS/MS) techniques. The Postdoctoral Fellow will also be responsible for communicating the results of these activities through manuscript publications and presentations at scientific meetings. Finally, the identified Fellow is also expected to constructively interact with Faculty, Staff, and Students within the Department and SMHS.

Minimum Requirements:

• Possess a recent Ph.D (6 years ago or less). or equivalent terminal degree in neuroscience, biochemistry, pharmacology, immunology, cell biology, or related discipline.

• Research experience in at least one of the following areas: murine models of disease, molecular biology or signal transduction.

• Minimum of one first (or co-first) author peer-reviewed journal publication.

• Submission of (1) a full Curriculum Vitae that includes education or other academic appointments, complete publication record and research skills listed in detail, (2) the contact information of three references, (3) a PDF copy of the most representative publication of the applicant’s previous research, and (4) a statement of research interest.

In compliance with federal law, all persons hired will be required to verify identity and eligibility to work in the US and to complete the required employment eligibility verification form upon hire.

Preferred Requirements:

• Demonstrated ability to independently complete complex research programs.

• Proficiency in scientific oral and written communication.

• Experience with multiparameter flow cytometry or mass spectrometry analysis.

• Familiarity with bioinformatics analysis of high-throughput datasets.

Review of applications will begin immediately. Position is open until filled. For more information or to apply visit https://www1.und.edu/finance-operations/human-resources-payroll/careers/secure/job-openings-external.cfm?category=2000+Academic&subcategory=2240+Post+Doctorate+Research+Fellow%3A . Search for JobID 5451 and click on the red button to apply.

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EEO Statement:

UND is an Equal Opportunity/Affirmative Action employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity or national origin. Women, minorities, veterans and individuals with disabilities are encouraged to apply. Applicants are invited to provide information regarding their gender, race and/or ethnicity, veteran’s status and disability status on the form found at http://und.edu/affirmative-action/apcontrolcard.cfm . This information will remain confidential and separate from your application.

ND Veteran’s Preference:

North Dakota Veterans claiming preference must submit all proof of eligibility by the closing date. Proof of eligibility includes a DD-214 and if claiming disabled status, a current letter of disability from the VA dated within the last 12 months.

Clery Statement:

In compliance with the Jeanne Clery Disclosure of Campus Security Policy and Campus Crime Statistics Act, the University of North Dakota publishes an Annual Security and Fire Safety Report. The report includes the university’s policies, procedures, and programs concerning safety and security, as well as three years’ of crime statistics for our campus. As a prospective employee, you are entitled to a copy of this report. The report and statistical data can be found online at http://und.edu/discover/_files/docs/annual-security-report.pdf. You may also request a paper copy of the report from the UND Police Department located at 3851 Campus Road, Grand Forks, ND 58202.

Confidentiality of Application Materials:

Note: Pursuant to NDCC 44-04-18.27, applications and any records related to the applications that identify an applicant are confidential, except records related to the finalists of the position, which are open to the public after the search committee has identified the top finalist.