招聘简介：

博士后研究人员

邀请博士后研究人员参加位于英国诺里奇的国际知名植物和微生物生物学研究所约翰·因尼斯中心（JIC）丹尼尔·齐伯曼博士的实验室，该研究所拥有最先进的科学设施和基础设施。

背景：

Zilberman实验室（https://zilbermanlab.net/）研究了DNA甲基化的遗传、功能和进化，这是一种调节植物、动物和其他真核生物基因表达的关键表观遗传机制。甲基化模式的正确遗传对人类健康和植物发育至关重要。

我们的团队在DNA甲基化研究领域处于领先地位超过十年，我们定期在最著名的多学科期刊上发表，包括自然、科学、细胞、elife和pnas。Zilberman集团的前几位成员现在担任独立的教师职位。

英文原文：

Postdoctoral Researchers

Applications are invited for Postdoctoral Researchers to join the laboratory of Dr Daniel Zilberman at the John Innes Centre (JIC), an internationally-renowned plant and microbial biology research institute featuring state-of-the-art scientific facilities and infrastructure, based in Norwich, UK.

Background:

The Zilberman laboratory (https://zilbermanlab.net/) studies the inheritance, function and evolution of DNA methylation, a key epigenetic mechanism that regulates gene expression in plants, animals and other eukaryotes. Proper inheritance of methylation patterns is essential for human health and plant development.

Our group has been at the forefront of DNA methylation research for over ten years, and we regularly publish in the most prominent multidisciplinary journals, including Nature, Science, Cell, eLife and PNAS. Several previous members of the Zilberman group now hold independent faculty positions.

The role:

The successful candidates will work on a project supported by the European Research Council to achieve a quantitative understanding of how nucleosomes, linker histones, and other chromatin components influence the accurate inheritance of DNA methylation patterns, and how DNA methylation in turn regulates nucleosomes and other aspects of chromatin structure. Arabidopsis thaliana will be the primary model, and we expect the resulting ideas and insights to be highly relevant to transcriptional control across eukaryotes.

Aspects of this project will involve genetic, genomic, biochemical, and bioinformatic approaches; candidates interested in using some or all of these techniques to explore DNA methylation-based epigenetics are encouraged to apply. This project will also entail a close collaboration with the Howard group at JIC to develop empirically supported mathematical models of DNA methylation-based epigenetic inheritance.

The ideal candidate:

The successful candidates will have a PhD (awarded or expected within 6 months) in Biological Sciences with a high-quality publication record and demonstrable scientific success in previous roles. Candidates should possess experience in molecular biology, as well as excellent communication and interpersonal skills. Prior experience in plant biology and epigenetics is desirable but not essential.

Additional information:

Salary on appointment will be within the range £31,250 to £38,100 per annum depending on qualifications and experience. Two full time posts are available, each for a period of two years, with a possibility of extension.

For further information and details of how to apply, please visit our web site http://jobs.jic.ac.uk or contact the Human Resources team on 01603 450462 or nbi.recruitment@nbi.ac.uk quoting reference 1003684.

We are an equal opportunities employer, actively supporting inclusivity and diversity. As a Disability Confident organisation, we guarantee to offer an interview to all disabled applicants who meet the essential criteria for this vacancy. The John Innes Centre is also proud to hold a Gold Award from Athena SWAN and is a member of Stonewall’s Diversity Champions programme.

The closing date for applications will be 5th June 2019.

The John Innes Centre is a registered charity (No. 223852) grant-aided by the Biotechnology and Biological Sciences Research Council and is an Equal Opportunities Employer.