招聘简介：

博士后：研究创伤性脑损伤和压力对神经退行性疾病小鼠模型的影响

·马萨诸塞大学医学中心

·地点：马萨诸塞州伍斯特市

·工作号码：7057238

·发布日期：2019年5月9日

·申请截止日期：开放至填写

职位描述

马萨诸塞大学医学中心的博斯科实验室对博士后研究员开放。我们的实验室是高度跨学科和协作的。我们位于马萨诸塞州伍斯特市大学校园内最先进的Albert Sherman转化科学中心。我们的研究重点是神经退行性变的分子机制，重点关注肌萎缩侧索硬化症（ALS），额颞叶痴呆（FTD）和创伤性脑损伤（TBI）模型中的应激反应受损（www.boscolab.com）。

英文原文：

Post-doc: investigating the effects of traumatic brain injury and stress in mouse models of neurodegenerative disease

· University of Massachusetts Medical Center

· Location: Worcester, MA

· Job Number: 7057238

· Posting Date: May 9, 2019

· Application Deadline: Open Until Filled

Job Description

The Bosco laboratory at the University of Massachusetts Medical Center has an open position for a post-doctoral fellow. Our laboratory is highly interdisciplinary and collaborative. We are located in the state-of-the-art Albert Sherman Center for translational science at the University Campus in Worcester, MA. Our research focuses on molecular mechanisms underlying neurodegeneration, with a focus on impaired stress response in models of amyotrophic lateral sclerosis (ALS), frontotemporal dementia (FTD) and traumatic brain injury (TBI) (www.boscolab.com).

The candidate should have a PhD in the biological sciences and extensive experience working with mice. The open project entails in vivo (mouse) work, cutting-edge fluorescence microscopy analyses including 2-photon and confocal microscopy, and deep sequencing. The candidate will need to demonstrate proficiency in animal (mouse) husbandry (breeding, genotyping, maintaining their own mouse colony), tissue sectioning, histological staining and imaging of tissue slices. Prior experience with neuroscience and mouse neuroanatomy is advantageous. Post-doctoral fellows are encouraged to secure their own funding and to write their own manuscripts, and will be mentored by the PI in grant-writing. The fellow will be trained to operate various fluorescence microscopes for their studies, and will receive guidance and support for RNA-sequencing analyses (if needed).

We are asking all candidates to provide their CV/resume, a cover letter and a brief research statement describing their experience and future goals. This position is for a post-doctoral fellow (first or second post-doc only) and not for a staff scientist.