招聘简介：

VIB是比利时法兰德斯的一家富有创业精神且充满活力的非营利性研究机构，专注于生命科学领域的突破性研究。 VIB-KULeuven癌症生物学中心（CCB）是位于比利时鲁汶大学医院校区的VIB研究部门之一。建行拥有11个研究小组，代表约200名国际研究人员，行政和技术合作者。 CCB的重点是揭示癌症的分子基础，并在适当的时候利用这些见解来开发新的治疗或诊断策略。

关于实验室

由Patrizia Agostinis领导的细胞死亡研究和治疗实验室寻求一位积极性高，技术精湛的博士后研究员加入该团队。我们的团队正在研究癌症和基质细胞中的自噬作为肿瘤微环境和抗肿瘤免疫的主要修饰因子。我们最近确定了肿瘤血管相关自噬在癌症传播和生长中的关键作用。我们现在有兴趣揭示自噬如何影响肿瘤 - 基质对话，特别关注肿瘤免疫监测和免疫治疗反应。我们的目标是追求创新和跨学科的研究主题，涵盖从综合组学到转化癌症免疫疗法的研究，以利用自噬调节机制获得治疗益处和改进免疫疗法。

职位描述

作为博士后，您将进行基础和临床前研究，重点关注基质细胞相关自噬在免疫监视和使用转基因小鼠模型的抗肿瘤免疫中的作用。您将为博士生提供超级支持和支持，为实验室的多个研究项目做出贡献，具有协作精神，并与合作者，临床医生，计算生物学家以及技术转让专家和行业合作者保持联系。您需要能够独立地组织和排除您的工作，对其进行全面记录，并以透明和专业的方式与团队沟通结果和经验。

英文原文：

VIB is an entrepreneurial and vibrant non-profit research institute in Flanders-Belgium with a clear focus on ground breaking research in life sciences. The VIB-KULeuven Center for Cancer Biology (CCB), is one of the research departments of VIB located at the University Hospital Campus in Leuven, Belgium. CCB hosts 11 research groups and represents about 200 international research-ers, administrative and technical collaborators. The focus of the CCB is to unravel the molecular basis of can-cer, and whenever suitable, exploit these insights to develop novel therapeutic or diagnostic strategies.

About the Lab

The Laboratory for Cell Death Research & Therapy, headed by Patrizia Agostinis, seeks a highly motivated and skilled Postdoctoral Researcher to join the team. Our team is studying autophagy in cancer and stromal cells as a main modifier of the tumor microenvironment and anti-tumor immunity. We recently defined a critical role for tumor vasculature-associated autophagy in cancer dissemination and growth. We are now interested in unravelling how autophagy impacts the tumor-stroma dialogue with particular focus on tumor immunosurvelliance and immunotherapy responses. Our goal is to pursue an innovative and interdisciplinary research theme, covering research from integrated omics to translational cancer immunotherapy, in order to harness autophagy regulated mechanisms for therapeutic benefits and for the improvement of immuno-therapy.

Job description

As a postdoc you will perform basic & preclinical research focused on the role of stromal cell-associated autophagy in immunosurveillance and anti-tumor immunity using transgenic mouse models. You will super-vise and support PhD students and contribute to several research projects of the lab, have a collaborative spirit and liaise with collaborators, clinicians, computational biologists, but also technology transfer experts and industrial collaborators. You need to be able to organise and troubleshoot your work independently, document it thoroughly and communicate results and experiences with the team in a transparent and pro-fessional manner.

Profile and skills

We are looking for a highly motivated, well organized and dynamic candidate with a high level of independ-ence and creative thinking.

You hold a PhD in cancer immunology or related fields

You have a publication track record in these fields with at least one first author publication

You are eager to learn new techniques and you show a keen interest and curiosity driven approach to

scientific questions

You have demonstrable practical skills in molecular/cellular biology, isolation and phenotyping on

immune cells, T cells analysis in vivo/ex vivo, high-end imaging, analysis of tumor

microenvironment. Knowledge and skills related to autophagy pathways is a plus

VIB Center for Cancer Biology

You have experience in working with deadlines and being involved simultaneously in multiple

projects

You are a team player with excellent oral and written English communication skills

You are able to guide PhD students and coordinate the projects between our teams

We offer

A 3 to 4 years position based on an annual contract with the possibility of renewal, and depending on a positive evaluation; the candidate will be expected to apply for personal postdoctoral fellowships

The job is available immediately, but the starting date is negotiable

Access to state-of-the-art infrastructure

A stimulating, research work environment where quality, professionalism and team spirit are

encouraged

The opportunity to interact with several world-class investigators at our VIB-KU Leuven Center for Cancer Biology (CCB), in Belgium (through our established network and research consortia) and abroad.

How to apply?

Please complete the online application procedure on VIB jobsite - see http://www.vib.be/en/jobs/Page... - and include:

A detailed CV, including a list of your scientific publications

An elaborate cover letter describing your motivation

Contact information of 2 referees

Applications sent by email will not be considered.

For more information, please contact Patrizia Agostinis.

Application deadline: July 30th, 2019.