招聘简介：

博士后免疫学研究员

·希望之城

·地点：加利福尼亚州杜阿尔特

·工作编号：7057371

·发布日期：2019年5月20日

·申请截止日期：开放至填写

职位描述

贝克曼希望之城研究所正在加利福尼亚州杜阿尔特希望之城的Leo D.Wang博士的实验室里寻找一位才华横溢的博士后研究员。

你喜欢免疫学，特别是T细胞受体信号？

你有兴趣应用这些知识来帮助开发新的癌症疗法吗？

您对设计、领导和实施自己的项目感到兴奋吗？

我们正在招募热情、积极的科学家，他们正在寻求一个快速、团队为基础的学术研究环境。我们在免疫肿瘤学部门的实验室专注于血液和免疫细胞如何发展、功能和与其他细胞的相互作用，第二个重点是血液干细胞如何变得恶性。我们使用质谱法来鉴定罕见的血干细胞和祖细胞群中的激活蛋白电路，包括治疗性嵌合抗原受体（car）T细胞，并将这一知识与基本免疫原理结合，以改进和设计新的治疗儿童癌症和血液疾病的方法。

英文原文：

Postdoctoral Fellow - Immunology

· City of Hope

· Location: Duarte, CA

· Job Number: 7057371

· Posting Date: May 20, 2019

· Application Deadline: Open Until Filled

Job Description

The Beckman Research Institute of City of Hope is looking for a talented Postdoctoral Fellow in the laboratory of Leo D. Wang, MD, PhD, at City of Hope, Duarte, CA.

Do you love immunology, particularly T cell receptor signaling?

Are you interested in applying that knowledge to help develop new cancer therapies?

Are you excited to design, lead, and implement your own projects?

We are recruiting enthusiastic, motivated scientists who are seeking a fast-paced, team-based academic research environment. Our lab in the Department of Immuno-oncology focuses on how blood and immune cells develop, function, and interact with other cells, with a second focus on how blood stem cells become malignant. We use mass spectrometry to identify activated protein circuits in rare blood stem and progenitor cell populations, including therapeutic chimeric antigen receptor (CAR) T cells, and combine that knowledge with fundamental immunological principles to improve and devise new therapies for pediatric cancers and blood disorders.

To learn more about our research, visit: www.leowanglab.org or

https://www.cityofhope.org/research/beckman-research-institute/research-departments-and-divisions/immuno-oncology/leo-wang-lab/leo-wang-lab-research.

Key Responsibilities

Design and lead multiple projects focused on understanding CAR signaling in brain-tumor-targeted CAR T cells, using canonical TCR signaling as a fundamental framework. Both in vitro and in vivo rodent work will be required.

Coordinate lab tasks and operations among multiple lab members, including ordering, inventory, and other essential lab functions.

Prepare laboratory reagents, chemicals, instruments, and maintain equipment.

Keep detailed and accurate logs of experiments from conception to analysis, as well as of lab inventory and rodent colonies.

Record data meticulously and analyze and synthesize results using industry standard application suites.

Help to prepare presentations and manuscripts for publication.

Initiate and maintain collaborations with other labs.

Travel to meetings to represent the lab and to present new data.

Basic education, experience and skills required for consideration:

Ph.D. in immunology or related field;

Expertise with flow cytometry, immunologic assays, cell culture, and molecular biology techniques is required;

Ability to work productively and meticulously;

Ability to develop cohesive team relationships;

Extensive prior experience in immunology or a closely related field;

Good oral and written communication skills;

Ability to structure tasks logically and effectively, organize, and set priorities;

Ability to respond effectively to constructive feedback;

Ability to analyze data statistically and to present it logically.

Preferred education experience and skills:

Experience with high-resolution imaging platforms and mass cytometry (CyTOF) or mass spectrometry is a plus;

Programming experience (R, Python) preferred.

Additional Information:

Ideal candidates will be highly motivated and have ambitions to further develop scientific and career skills. They will have a desire to be challenged and to learn new scientific strategies and techniques.

In addition to competitive compensation and benefits, candidates will have the opportunity to learn and to develop research publications and presentations, independent grant applications, and independent projects that they can take with them when they leave the lab.

Candidates will receive training in the safe handling of toxic chemicals, biohazards, animals, radiation, and other reagents.

City of Hope is committed to creating a diverse environment and is proud to be an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, religion, color, national origin, sex, sexual orientation, gender identity, age, status as a protected veteran, or status as a qualified individual with disability.

City of Hope is committed to creating a diverse environment and is proud to be an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, religion, color, national origin, sex, sexual orientation, gender identity, age, status as a protected veteran, or status as a qualified individual with disability.