招聘简介：

在线粒体RNA的结构生物化学博士后研究（奖学金）

卡罗林斯卡学院（AI）

斯德哥尔摩，瑞典

张贴约3天，7月20 agoexpires 2019

细胞与分子生物学部（CMB）是一部具有强烈的重点放在基础科学。研究和教育conducts中巴在细胞生物学、分子生物学、发育生物学、干细胞生物学、肿瘤生物学和感染。

分

提供一个hällberg实验室是国际环境刺激的互动。我们是一部在细胞和分子生物学在斯德哥尔摩Karolinska研究所，瑞典，是世界领先的一́s医科大学。实验室位于最近开了一biomedicum，艺术研究的建设。

我们是在寻求照顾者有兴趣在学习和博士后研究员）的线粒体基因组的结构细胞生物学分离和隔离。该项目是一个多学科协作的一部分，由Alice Wallenberg基金会和由克努特，在斯德哥尔摩大学Alexey amunts在组和组rorbach和乔安娜马丁hällberg在卡罗林斯卡研究所。

关税

该项目的目的是在ribosomal structurally和biochemically到成熟的过程。在《hällberg subproject协作，在很早的治疗步骤（rRNA成熟的自然是共同转录与早期的处理步骤和他们的协调与结合蛋白（ribosomal和成熟的因素。涉及的主要技术是电子显微镜（低温电磁），macromolecular crystallography和生物化学。在项目中，我们将使用这两个国家和国际来源的低温EM和同步辐射设施。此外，我们将研究使用冷冻EM，卡罗林斯卡学院的设施，一个新的3D EM krios 300 kV（K3 120c是该探测器）和安装在一个低温2019年秋（FIB / SEM是安装的最后一年。

英文原文：

Postdoctoral studies in mitochondrial RNA structural biochemistry (scholarship)

Karolinska Institutet (KI)

Stockholm, Sweden

Posted about 3 days agoExpires on July 20, 2019

The Department of Cell and Molecular Biology (CMB) is a department with a strong focus on basic science. CMB conducts research and education in cell biology, molecular biology, developmental biology, stem cell biology, cancer and infection biology.

Division

The Hällberg laboratory is offering a stimulating, interactive international environment. We are part of the Department of Cell and Molecular Biology at the Karolinska Institutet in Stockholm, Sweden, one of the world ́s leading medical universities. The lab is located in the recently opened Biomedicum, a state-of-the-art research building.

We are seeking a highly motivated and enthusiastic postdoctoral fellow interested in studying the structural cell biology of mitochondrial genome separation and segregation. The project is part of a multi-disciplinary collaboration – financed by the Knut and Alice Wallenberg Foundation – between the groups of Alexey Amunts at Stockholm University and the groups of Joanna Rorbach and Martin Hällberg at the Karolinska Institutet.

Duties

The project aims to structurally and biochemically characterize the ribosomal maturation process. The Hällberg subproject in the collaboration focuses on the very earliest mito-rRNA maturation steps that occur co-transcriptionally and involves the early processing steps and their coordination with binding of ribosomal proteins and maturation factors. Main techniques involved are electron microscopy (cryo-EM), macromolecular crystallography and biochemistry. In the project, we will utilize both national and international synchrotron sources and cryo-EM facilities. Furthermore for cryo-EM, we will utilise Karolinska Institutet’s new 3D-EM facility with a Krios 300 kV (K3 detector) and Talos 120C to be installed during the autumn of 2019 with a cryo-FIB/ SEM to be installed in the end of the year.

Entry requirements

We are looking for highly motivated, independent and driven candidates. The successful applicant will have a background either in structural biology or RNA/RNA-protein biochemistry willing to learn or develop skills in state-of-the-art techniques for studying the structural biochemistry of protein-RNA complexes. A documented ability to independently carry out experimental research projects is required, as are good communication skills in spoken and written English.

Scholarships for postdoctoral qualification can be established for foreign researchers who place their qualifications in Sweden. The purpose of scholarships for postdoctoral qualification is to promote internationalization and contribute to research qualification after a doctorate or equivalent.

A scholarship for carrying out postdoctoral research can be granted for a maximum of two years within a four year period following the receipt of a doctoral degree or equivalent.

To be eligible for a postdoctoral scholarship, the person must have obtained a doctorate or a foreign degree deemed to be equivalent to a doctorate.

The head of the department determines whether their previous training and scholarly qualifications correspond to a Swedish doctorate or higher.

Type of scholarship

The amount is tax free and it is set for twelve months at a time, paid out on a six months basis. In exceptional cases, shorter periods may be acceptable.

Application process

An application must contain the following documents in English or Swedish:

· A complete curriculum vitae, including date of the thesis defence, title of the thesis, previous academic positions, academic title, current position, academic distinctions, and a summary of skills and experience

· A complete list of publications

· A brief summary of current work (no more than one page)

The application is to be submitted on the Varbi recruitment system. Applications will be screened continuously and we might start the interview process before the last day of application.

Karolinska Institutet is one of the world’s leading medical universities. Its vision is to significantly contribute to the improvement of human health. Karolinska Institutet accounts for the single largest share of all academic medical research conducted in Sweden and offers the country’s broadest range of education in medicine and health sciences. The Nobel Assembly at Karolinska Institutet selects the Nobel laureates in Physiology or Medicine.

Pursuant to the regulations of the Swedish National Archives, applications are kept on file for two years after the appointment has gained legal force. The regulations do not apply to attachments that have been printed or otherwise published.

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