招聘简介：美国霍华德·休斯医学研究所生物信息学或生物学博士后招聘

英文原文：

Job Summary:

The Howard Hughes Medical Institute has a postdoctoral position available in the laboratory of Dr. Norbert Perrimon at Harvard Medical School. The Perrimon lab uses Drosophila as a model system to characterize the mechanisms underlying communication between cells, tissues, and organs, more specifically, focusing on the composition & organization of signaling networks, the cell signaling in time and space as well as the communication between organs. The lab is actively generating such data sets of omics scale and this position will involve developing new algorithms analyzing these datasets. You will work collaboratively with a small team of biologists and programmers in a fast-paced environment.

About HHMI

Howard Hughes Medical Institute (HHMI) is a science philanthropy whose mission is to advance biomedical research and science education for the benefit of humanity. We empower exceptional scientists and students to pursue fundamental questions about living systems, and work to share scientific discoveries with researchers, students, and science-curious individuals around the world.

Founded in 1953 by aviator and industrialist Howard R. Hughes, HHMI is headquartered in Chevy Chase, Maryland, and employs more than 2,500 people across the U.S. Visit hhmi.org/careers to learn more about working at HHMI.

Principle responsibilities:

o Design and implement reusable bioinformatics analysis pipelines for processingRNA-seq, single-cell RNA-seq, genomics and proteomics data.

o Integrate computational methods/pipelines with high performance computing clusters.

o Establish and customize genomic, proteomics databases and provide batch analysis utilities that make use of these resources.

o Develop custom databases and web portals for managing raw and processed experimental data.

o Develop APIs of DRSC/TRiP existing databases.

o Collaborate closely with Investigator and lab members on research projects including defining the scope of the collaboration, researching the scientific topics and implementing the appropriate bioinformatics solutions that meet project timelines.

o Coordinate and collaborate with other bioinformaticians, biostatisticians, information technology professionals, and interdepartmental project teams.

o Properly document the procedures used in computational analysis and provide summary report of result.

o Collaborate closely with Investigator and lab members on research projects including defining the scope of the collaboration, researching the scientific topics and implementing the appropriate bioinformatics solutions that meet project timelines.

Preferred Qualifications:

o Doctoral degree in Bioinformatics or in biology with extensive experience analyzing omics data.Strong background in programming and algorithms. Fluent in one programming language (Python, C, C++ or Java) and familiarity with scripting languages (bash, Perl)

o Experience using genome alignment software (bowtie2, bwa, tophat, etc.) is desired.

o Familiarity with programming techniques for analyzing data sets.

o Experience working with BIG DATA (eg. NGS data in multi-TB scale).

o Experience using relational databases, SQL and / or structured data formats.

o Knowledge of Unix operating system, terminal and bash is a plus.

o Web programming experience (PHP, Django, JavaScript, JQuery, JSON, REST API) is a plus.

o Excellent oral and written communication skills as well as the ability to collaborate effectively with a diverse team.

Please provide the names and contact information for three references.