加拿大英属哥伦比亚大学2021年招聘博士后职位（神经炎症研究）

Postdoctoral fellow in neuroinflammation research

With support from funding agencies as well as privately funded initiatives, the Neuroinflammation Research Lab is growing. We are expanding our research efforts and are looking for committed team players interested in making a difference in health research and the lives of individuals living with neurodegenerative disorders including MS.

Focus project areas:

•Imaging and therapeutic strategies in novel preclinical models of neuroinflammatory disorders

•Limiting inflammation and activation of the blood-brain barrier

•Biomarker analyses in patient cohorts

•Environmental influence upon inflammatory and neuroprotective proteins and processes relevant to multiple sclerosis and other neurodegenerative disorders.

Project and Candidates:

Candidates with expertise in neuroscience/immunology related cell culture, molecular biology, murine preclinical and behavioural models are encouraged to apply. The successful candidate will undertake a research project aimed to examine factors that regulate neuroprotective factors both in the peripheral immune and within the central nervous system. Studies will span basic cell analyses through to more complex models and ultimately translation of these findings to human systems and disease.

Training & expectations:

Major areas of focus will include inflammatory mediators, oxidative stress, environmental stressors, immune populations, neurodegeneration and repair. The candidate should have a strong record of independent work, excellent writing abilities as well as a demonstrated proficiency in several of the following:

•Cell culture and aseptic technique, preferably involving both isolation and maintenance of rodent primary cultures as well as cell lines.

•Ability to perform and troubleshoot a wide variety of molecular and cellular biology techniques, including many of the following: • RNA/DNA isolation, quantitative PCR, transfection, siRNA knockdown and cDNA construct knockin, flow cytometry, immunohisto- and cytochemistry on cells as well as frozen and formalin-fixed, paraffin embedded tissues, ELISA, protein isolation and western blotting;

•A comprehensive understanding of experimental design and assay optimization is important.

•Experience performing fluorescence and light microscopy; conventional and/or confocal

•Willingness to work with small rodents is essential. Able to carry out and oversee procedures involving small rodents including immunization/injections, necropsy, blood sampling, and minor surgical procedures involved in animal surgery; applicants with experience in preclinical models of neurodegenerative diseases including MS are especially encouraged to apply.

•Maintenance/monitoring of colonies of transgenic animals, including colony breeding, screening and management.

Interested applicants should send a CV and statement of interests to jquandt@pathology.ubc.ca. Applications will be reviewed starting April 21, 2021 on a rolling basis and the position will stay open until filled.

For more information please see www.quandtlab.com

This posting is for the UBC Vancouver campus in British Columbia, Canada.

Please refer to reference number NC-54569 during correspondence about this position. Please visit the researcher profile of the supervisor for this position to learn more about their research.

Equity and diversity are essential to academic excellence. An open and diverse community fosters the inclusion of voices that have been underrepresented or discouraged. We encourage applications from members of groups that have been marginalized on any grounds enumerated under the B.C. Human Rights Code, including sex, sexual orientation, gender identity or expression, racialization, disability, political belief, religion, marital or family status, age, and/or status as a First Nation, Metis, Inuit, or Indigenous person.

About UBC

The University of British Columbia is a global centre for research and teaching, consistently ranked among the top 20 public universities in the world. Since 1915, UBC’s entrepreneurial spirit has embraced innovation and challenged the status quo. UBC encourages its students, staff and faculty to challenge convention, lead discovery and explore new ways of learning. At UBC, bold thinking is given a place to develop into ideas that can change the world.

Postdoctoral Fellows at UBC Vancouver

UBC is home to over 900 postdocs spanning all faculties and units across two campuses and a variety of affiliated hospitals, research centres, and sites, providing unparalleled opportunities to learn, discover and contribute in one’s own way. UBC’s Postdoctoral Fellows Office (PDFO) is committed to supporting the lives and career aspirations of our Postdocs, with the goal of enriching their experience at UBC and preparing them for the future. In addition to providing support and advocacy for all postdocs, the PDFO is dedicated to providing professional development opportunities that foster the development of soft skills needed in today’s professional environments, helping them secure future careers in their chosen fields.

About Vancouver

Vancouver is a dynamic, cosmopolitan and progressive city, consistently ranked as one of the top cities to live in the world. Canada’s third largest city has it all: sea, parks, mountains, beaches, and four seasons per year, including beautiful summers and mild, wet winters with snow in the mountains. It’s the perfect backdrop to your academic research.

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