英国华威大学2022年招聘博士后（有机合成和药物化学方向）

Research Fellow (103844-0322) . Job Reference: 1883163

University Of Warwick

Description

Vacancy Type/Job category

Research Only

Department

Life Sciences

Salary

£31,406 - £40,927 per annum

Location

University of Warwick, Coventry

Vacancy Overview

Full time, fixed term position available immediately. Funding is restricted to end by 30/11/2022 and might have to be shortened depending on the starting salary of the successful candidate.

Applications are invited for a postdoctoral research fellow to work under the supervision of Dr Elizabeth Fullam, in collaboration with Professor Matthew Gibson (Department of Chemistry) and Dr Rob Young (Blue Burgundy Drug Discovery Consulting) on a project which involves the design, synthesis and development of new molecules for the treatment of tuberculosis (TB), one of the leading causes of death from a single infectious disease in the world. In this project, the focus will be on organic synthesis and medicinal chemistry. We will evaluate these new inhibitors using biophysical assays and against Mycobacterium tuberculosis and mammalian cell lines. The project is funded by the Warwick-Wellcome Translational Partnership and is available immediately.

Applicants should possess, or expect to shortly obtain, a PhD and have a proven track record in organic/medicinal chemistry with extensive experience of the design and synthesis of small molecules. You will have experience in synthetic chemistry and organic chemistry and demonstrate competence and proficiency in this area. You should be able to adapt existing synthetic techniques and establish new strategies and methodologies. An understanding of inhibitor optimisation and determining structure-activity relationships of small molecules would be beneficial. You should be capable of working under your own initiative but also collaboratively with researchers from a range of different disciplines, so excellent communication, organisational and team skills are required.

If you have not yet been awarded your PhD but are near submission or have recently submitted your PhD, any offers of employment will be made as Research Assistant on level 5 of the University grade structure (£30,497). Upon successful award of your PhD and evidence of this fact, you will be promoted to Research Fellow on the first point of level 6 of the University grade structure (£31,406 pa).

To explore the post further, or for any queries you may have please contact e.fullam@warwick.ac.uk Further information about Dr Elizabeth Fullam's research group can be found at https:// www2.warwick.ac.uk/fac/sci/lifesci/research/pathbac/ Informal enquiries can be made directly to Dr Elizabeth Fullam (e.fullam@warwick.ac.uk) Further information about the laboratory can be found here: https:// www2.warwick.ac.uk/fac/sci/lifesci/research/pathbac/

Interviews will be held as soon as possible after the closing date TBC. Short- listed candidates will be expected to give a presentation of their previous research relevant to this project as part of this interview process.

Job Description

JOB PURPOSE

This research position will investigate whether it is possible to hijack Mycobacterium tuberculosis nutrient transporters. The goal will be to design, synthesise and evaluate new inhibitors against Mtb.

In addition, the role will involve assisting the project leader to support the work of the department and develop and enhance its reputation, both internally and externally. Where appropriate, the role will involve working with project collaborators to ensure the successful execution of the project, and the dissemination of project results.

DUTIES & RESPONSIBILITIES

Research

• Help establish a sound research base within the department in order to assist the development of research objectives and proposals for own or joint research.

• Conduct individual and collaborative research projects within the conditions of the contract.

• To publish research outcomes in appropriate journals of international standing and to publish and disseminate the result of research to other reputable outlets.

• Translate knowledge of advances in the subject area into research activity.

• May contribute to preparing proposals and applications to external bodies, e.g. for funding and contractual purposes, to support a developing research agenda.

• May present information on research progress and outcomes to bodies supervising research, e.g. steering groups.

•Analyse data and present results in an appropriate format (oral, written) in a language appropriate for the audience, which may include the project leads, lab members, departmental and external colleagues, funders and the general public.

• May contribute to the preparation of papers for steering groups and other bodies.

• Communicate complex information (orally and in writing) and material of a specialist or highly technical nature.

• Continually update own knowledge and understanding in field or specialism.

• To work within the requirements of the Research Governance policies of the University.

• To stay current with scientific literature in the research field.

• To work within budget restraints.

• To design, synthesise and evaluate new molecules for activity against Mycobacterium tuberculosis.

Teaching and Learning Support

• Assist in the supervision of student projects and the development of student research skills.

• May be involved in the assessment of student knowledge and supervision of projects.

Administration and other activities

• May be required to attend departmental meetings and to participate (where necessary) in other committees and working groups within the department, the faculty and the University.

• Ensure compliance with health and safety in all aspects of work.

• To engage in professional development activities.

• To participate in relevant professional activities.

• Work within budget constraints.

• Management of the project on a day to day basis, including managing equipment and purchasing consumables and maintenance issues. Monitoring progress and advising the PI of any issues that are likely to lead to a delay in the project.

• Assist with communication of the group's research in outreach activities or the wider community.

• Ensure compliance with health and safety in all aspects of work, and when appropriate undertake risk assessments.

The duties and responsibilities outlined are not intended to be an exhaustive list but provide guidance on the main aspects of the job. You will be required to be flexible in your duties.

Person Specification

The Person Specification focuses on the knowledge, skills, experience and qualifications required to undertake the role effectively. This is measured by (a) Application Form, (b) Test/Exercise, (c) Interview, (d) Presentation.

Essential Criteria 1

Good honours degree and possession of a PhD or equivalent in relevant discipline. (a, c)

Essential Criteria 2

Proven ability in research and evidence of quality research output inorganic/medicinal chemistry. (a, c)

Essential Criteria 3

A developing research profile with the ability to communicate results effectively and publish and/or produce high quality research output. (a, c, d)

Essential Criteria 4

Sufficient breadth or depth of specialist knowledge in synthetic/organic chemistry and of research methods and techniques to work within established research programmes. (a, c, d)

Essential Criteria 5

Good effective communication (oral and written) skills, presentation and training skills. (a, c, d)

Essential Criteria 6

Experience of working independently or as part of a team, able to make decision and organise and prioritise own workload. (a, c, d)

Essential Criteria 7

Exceptional time management, organisational and self-motivational skills with ability to act on own initiative. (a, c, d)

Essential Criteria 8

Have experience of supervising other research colleagues or PhD students. (a, c)

Essential Criteria 9

Experience of working with the PI to analyse the requirements of a project, including setting the project milestones. (a, c)

Essential Criteria 10

Experience of working independently or as part of a team, making decisions and organising and prioritising own workload. (a, c, d)

Essential Criteria 11

Ability to keep meticulous notebook records and have good attention to detail. (a, c, d)

Essential Criteria 12

Excellent IT skills. (a, c, d)

Essential Criteria 13

Good problem-solving skills knowing when to refer to others for advice. (a, c, d)

Desirable Criteria 1

Ability or potential to contribute to the development of funding proposals in order to generate external funding to support research projects. (a, c)

Desirable Criteria 2

Experience with general biophysical techniques e.g. MST, SPR. (a, c)

Desirable Criteria 3

An understanding of determining structure-activity relationships of small molecules. (a, d)

Further Particulars

For further information about the University of Warwick, please read our University Further Particulars.

For further information about the department, please visit the departmental website.

Right to work in the UK If you do not yet have the right to work in the UK and/or are seeking sponsorship for a Skilled Worker visa in the UK points-based immigration system please click on this link which contains further information about obtaining right to work in the UK and details about eligibility for sponsorship for a Skilled Worker Visa.

The University of Warwick provides an inclusive working and learning environment, recognising and respecting every individual's differences. We welcome applications from individuals who identify with any of the protected characteristics defined by the Equality Act 2010.

Recruitment of Ex-Offenders Policy

As an organisation using the (DBS) Disclosure and Barring Service to assess applicants' suitability for positions of trust, the University of Warwick complies with the DBS Code of Practice and undertakes not to discriminate unfairly against any subject of a Disclosure on the basis of a conviction or other information revealed. More information is available on the University's Vacancy pages and applicants may request a copy of the DBS Code of Practice.

Closing Date

14 Mar 2022

更多最新博士后招收信息请关注博士后招聘网微信公众号（ID：boshihoujob）