瑞典哥德堡大学2022年招聘博士后职位（抗生素耐药性）

Postdoctoral Fellow In Antibiotic Resistance

Göteborg University

Description

We seek a PhD for a full time postdoctoral position (24 months) within the research group led by Professor Joakim Larsson, Department of Infectious Diseases, Institute for Biomedicine, Sahlgrenska academy at the University of Gothenburg, Sweden. The focus of the research group is on antibiotic resistance development, particularly the role of the external environment. The group consists of 1 professor, 2 associate professors, 6 postdoctoral fellows, 1 PhD students, 1 biologist, 1 research assistant, a guest researcher as well as master students. (https: // www. gu.se/en/biomedicine/about-us/department-of- infectious-diseases/joakim-larsson-group). Larsson also leads the Centre of Antibiotic Resistance Research at University of Gothenburg (CARe; www. gu.se/en/care) with over 100 researchers. The group has extensive collaboration with other universities, nationally and internationally. The research is interdisciplinary and has significant funding through e.g. the Swedish Research Councils VR and Formas

Subject area

Antibiotic resistance.

Subject area description

Most of the resistance genes that cause problems in the clinic today seem to originate from harmless, environmental bacteria. Our group studies the driving forces behind this development, particularly the effects of low levels of antibiotics and antibacterial biocides in wastewaters from hospitals, municipalities and industries (see Larsson's website). In some sub-projects, we study the evolutionary relationship between resistance genes in environmental bacteria and pathogens, and search for new forms of resistance in different environments using both bioinformatic methods as well different large-scale functional screens. We also study how analyses of resistant bacteria in sewage can inform predictions of the local, clinical resistance situation. A better knowledge about all these processes and drives will be valuable to be assess and respond to threats to our health. We are now looking for a postdoctoral fellow who is interested in taking on the task to experimentally explore the environmental dimensions of antibiotic resistance.

Duties

Depending on the applicant's background, he/she is expected to conduct experimental research, addressing one or several of the research areas mentioned above. This could for example include exposing bacteria or more complex microbial communities to different selective agents or mixtures/wastewaters, followed by studies of selection and/or other processes. The work can also involve identifying and characterizing novel, mobile resistance genes in different environments. Methods that could prove valuable include environmental sampling, culturing of bacteria, resistance phenotyping, functional metagenomics, gene expression studies in bacteria, functional metagenomics, various methods related to recombinant DNA-technology such as vector construction, cloning and induced constitutive and inducible expression of exogenous proteins in bacteria, gene-knockout, inverse PCR, RT-PCR, qRT- PCR, epic-PCR, bioinformatic analyses of DNA-sequence data generated via different technologies, etc. Within the group there is already competence within e.g. bioinformatics, microbiology, molecular biology and environmental sciences, and we collaborate closely with clinicians, analytical chemists as well as with scientists outside the natural science domain. The work is expected to be conducted in collaboration, hence complementary expertise is valuable. The work also includes authoring/co-authoring scientific publications and presenting research at international scientific conferences.

Eligibility

The eligibility criteria for employing teaching staff are set out in Chapter 4 of the Higher Education Ordinance and in the Appointment Procedure for Teaching Posts at the University of Gothenburg.

To be eligible for appointment as a postdoc, the applicant is required to have a doctoral degree, a doctoral degree in art or a foreign degree that is deemed to be equivalent to a doctoral degree. This eligibility requirement must be met before the employment decision is made.

In the first instance, those who have completed their degree no more than three years prior to the end of the application period shall be considered. Those who have completed their degree more than three years prior to the end of the application period may also be considered in the first instance if special grounds exist. Special grounds relate to leave of absence due to illness, parental leave, commissions of trust within union organisations, service within the defence services or other similar circumstances, as well as clinical service or service/assignment relevant to the subject area.

Assessment criteria

Regulations for the evaluation of qualifications for academic positions are given in Chapter 4, Section 3 - 4 of the Higher Education Ordinance.

PhD in relevant area, as well as excellent scientific production in relation to the time passed since completing PhD are required. A high degree of independence including extensive experience of practical molecular and microbiological analyses with the techniques indicated, experience from relevant research on antibiotic resistance, previous international postdoc experience, excellent communicative skills particularly regarding verbal and written scientific English, a developed way of critical thinking, experience from working at different labs and an ability to work successfully in a group are all additional qualifying criteria.

Employment

The employment is full time and temporary, two years with the possibility of one year's extension, with placement at the Institute of Biomedicine. First day of employment as agreed.

Contact information

If you have any questions about the position, please contact Joakim Larsson, Professor. E-mail: joakim.larsson@fysiologi.gu.se

Unions

Union representatives at the University of Gothenburg can be found here: https: // www. gu.se/om-universitetet/jobba-hos-oss/hjalp-for-sokande

Application

Submit your application via the University of Gothenburg's recruitment portal by clicking the “Apply” button. It is your responsibility to ensure that the application is complete as per the vacancy notice, and that the University receives it by the final application deadline.

The application should contain:

- A cover letter giving a brief description of previous research experience, and a motivation to why you are applying

- A CV including a list of publications

- Proof of completed PhD

- Contact details of two references

Applications must be received by: 2022-05-03

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